Bhanurekha was born in the Tamil-speaking Ganesan household on October 10, 1954. Her dad was the popular Tamil actor, Gemini, while her mom was a popular Telugu actress, Pushpavalli. She has seven sisters and one brother. One of her sisters is Dr. Kamala Selvaraj, while another one, Radha, lives in San Francisco with a son named Naveed, who is being readied to act in Bollywood movies.
No stranger to the tinsel screen, Bhanurekha acted in a Telugu movie 'Rangula Ratnam' as Baby Bhanurekha along with her mom during 1966, which was subsequently re-made and released in Hindi during 1976 as Rangila Ratan (1976). She acted in one more Telugu as well as one Kannada movie (Amma Kosam and Goadalli CID 999 respectively) before re-locating to Bombay.