U.S. Route 45

U.S. Route 45 is a north-south highway in the eastern United States, running 1,297 miles through 7 states from Mobile, Alabama to Ontonagon, Michigan. This is a list of cities and attractions along the highway, from south to north.

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1

Mobile, Alabama

Mobile, Alabama

2

Waynesboro, Mississippi

Waynesboro, Mississippi

3

Quitman, Mississippi

Quitman, Mississippi

4

Clarkco State Park, Mississippi

Clarkco State Park, Mississippi

5

Meridian, Mississippi

Meridian, Mississippi

6

Macon, Mississippi

Macon, Mississippi

7

Columbus, Mississippi

Columbus, Mississippi

8

West Point, Mississippi

West Point, Mississippi

9

Aberdeen, Mississippi

Aberdeen, Mississippi

10

Amory, Mississippi

Amory, Mississippi

11

Okolona, Mississippi

Okolona, Mississippi

12

Tombigbee State Park, Mississippi

Tombigbee State Park, Mississippi

13

Tupelo, Mississippi

Tupelo, Mississippi

14

Brices Cross Roads National Battlefield Site

Brices Cross Roads National Battlefield Site

15

Booneville, Mississippi

Booneville, Mississippi

16

Corinth, Mississippi

Corinth, Mississippi

17

Shiloh National Military Park

Shiloh National Military Park

18

Selmer, Tennessee

Selmer, Tennessee

19

Henderson, Tennessee

Henderson, Tennessee

20

Pinson Mounds State Archaeological Park, Tennessee

Pinson Mounds State Archaeological Park, Tennessee

21

Jackson, Tennessee

Jackson, Tennessee

22

Humboldt, Tennessee

Humboldt, Tennessee

23

Trenton, Tennessee

Trenton, Tennessee

24

Union City, Tennessee

Union City, Tennessee

25

Big Cypress Tree State Park, Tennessee

Big Cypress Tree State Park, Tennessee

26

Martin, Tennessee

Martin, Tennessee

27

Fulton, Kentucky

Fulton, Kentucky

28

Mayfield, Kentucky

Mayfield, Kentucky

29

Paducah, Kentucky

Paducah, Kentucky

30

Metropolis, Illinois

Metropolis, Illinois

31

Fort Massac State Park, Illinois

Fort Massac State Park, Illinois

32

Mermet Lake State Fish and Wildlife Area, Illinois

Mermet Lake State Fish and Wildlife Area, Illinois

33

Cache River State Natural Area, Illinois

Cache River State Natural Area, Illinois

34

Vienna, Illinois

Vienna, Illinois

35

Shawnee National Forest

Shawnee National Forest

36

Harrisburg, Illinois

Harrisburg, Illinois

37

Hamilton County State Fish and Wildlife Area, Illinois

Hamilton County State Fish and Wildlife Area, Illinois

38

Fairfield, Illinois

Fairfield, Illinois

39

Flora, Illinois

Flora, Illinois

40

Louisville, Illinois

Louisville, Illinois

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