A relatively common trope in horror films and psychological thrillers, the concept of human experiments is truly horrific due to the realities of their existence. From World War II Nazi experiments to the birth of psychology field testing, the implantation of testing humans has resulted in a lot of suffering, but also a lot of knowledge about human behavior.
Therefore, the of human experimentation often results in two sides – that the overall good of knowledge counterbalances anything bad that can come out of the experiment, which is the mentality commonly seen in the experimenter, and the counterargument that nothing good can come out of anything bad is generally led by the subjects or victims.
From 1930's Frankenstein to 1960's French science fiction to today's exploitation of horror films as seen in the "Saw" and "Human Centipede" franchises, the theme has had a long tradition.