Taffy Sinclair makes her first appearance in the book The Against Taffy Sinclair Club. Taffy was the prettiest girl in Mark Twain Elementary and most of the boys had crushes on her. When she begins developing more than the other girls in school, Jana and the other girls create the club. The rivalry takes an especially ugly turn when jealous Jana writes an "expose" on Taffy in the school newspaper.
Taffy also becomes an actress in a soap opera and befriends Raven Blaine, a famous teen idol with whom she co-stars in the soap opera. Toward the end of the series, she is not a prominent character anymore because she is in Los Angeles, working as an actress. Jana implies that toward the end, she and the rest of The Fabulous Five had become civil with Taffy, most likely because they had The Fantastic Foursome rivalry to focus on. In a chapter of Yearbook Memories (Super Edition 4), Jana recounts how she and Taffy resolved their differences and grew to respect one another.