Andrea Donna de Matteo, called Drea (pronounced "dray"), was born on January 19, 1972 in Queens, New York, into an affluent family, the youngest of three children and the only girl. She is the daughter of Donna, a playwright and playwriting teacher at HB Studio in New York, and Albert A. De Matteo, a furniture manufacturer. She is of Italian descent. De Matteo spent her early childhood in Queens, and the family then moved to the Upper East Side in Manhattan, into Aretha Franklin's former townhouse.
De Matteo decided to pursue a directing career at NYU's Tisch School of the Arts, perhaps because of the brief moment when, as a girl, she was brought onstage out of the audience and dazzled by the stage lights when she was seeing the play "Cats," perhaps because of her mother's involvement in the entertainment business. Once she was in school, however, it was the acting classes which attracted her greatest interest, and she decided on an acting career. After a screen debut in an obscure in
